Vildagliptin CAS 274901-16-5
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2019-12-20 15:17
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Product details
Product Description:
Product Name: Vildagliptin CAS NO:274901-16-5
Synonyms:
Galvus; Laf 237; Vildagliptin API;
(2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile;
(-)-(2S)-1-[[(3-Hydroxytricyclo[3.3.1.1(3,7)]dec-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile;
1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine;
NVP-LAF 237;
2-Pyrrolidinecarbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)-;
(S)-1-[2-[(3-Hydroxyadamant-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile;
(S)-1-(2-(((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile;
(2S)-1-((3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile;
(2S)-1-[N-(3-Hydroxyadamantan-1-yl)glycyl]pyrrolidine-2-carbonitrile;
1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile;
Chemical & Physical Properties
Appearance : White crystalline powder
Assay : ≥99.0%
Density: 1.27g/cm3
Melting Point: 148.0℃~152℃
Boiling Point: 531.3℃ at 760 mmHg
Flash Point: 275.1℃
Refractive Index: 1.564
Vapor Pressure: 0mmHg at 25°C
PSA: 76.36000
LogP: 1.50308
Solubility: DMSO (Slightly), Methanol (Slightly).
Category: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Safety Information
HS Code: 2933990090
Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Application: Vildagliptin is a dipeptidyl peptidase-4 inhibitor class of oral antidiabetic drugs used to treat type 2 diabetes mellitus. Vildagliptin is the only substance that can inhibit glucagon in both hyperglycemia and hypoglycemia. Aside from their use in type 2 diabetes, Vildagliptin have positive cardiovascular and anti-inflammtatory effects and Antidiabetic.
Glyptins are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase.
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